OGG1 FISH Probe
The OGG1 FISH probe is designed to hybridize to the OGG1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| OGG1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| OGG1-20-RE | 20 (40 μL) | 200 μL |  |
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| OGG1-20-GO | 20 (40 μL) | 200 μL |  |
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| OGG1-20-GR | 20 (40 μL) | 200 μL |  |
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| OGG1-20-AQ | 20 (40 μL) | 200 μL |  |
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| OGG1-20-DIG | 20 (40 μL) | 200 μL |  |
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| OGG1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008]
Gene Details
Gene Symbol: OGG1
Gene Name: 8-oxoguanine DNA Glycosylase
Chromosome: CHR3: 9791627-9808353
Locus: 3p25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: OGG1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: OGG1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping