NXF1 FISH Probe
The NXF1 FISH probe is designed to hybridize to the NXF1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NXF1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NXF1-20-RE | 20 (40 μL) | 200 μL |  |
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| NXF1-20-GO | 20 (40 μL) | 200 μL |  |
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| NXF1-20-GR | 20 (40 μL) | 200 μL |  |
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| NXF1-20-AQ | 20 (40 μL) | 200 μL |  |
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| NXF1-20-DIG | 20 (40 μL) | 200 μL |  |
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| NXF1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NXF1
Gene Name: Nuclear RNA Export Factor 1
Chromosome: CHR11: 62559597-62572964
Locus: 11q12.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NXF1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NXF1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping