NR3C2 FISH Probe
The NR3C2 FISH probe is designed to hybridize to the NR3C2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NR3C2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NR3C2-20-RE | 20 (40 μL) | 200 μL |  |
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| NR3C2-20-GO | 20 (40 μL) | 200 μL |  |
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| NR3C2-20-GR | 20 (40 μL) | 200 μL |  |
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| NR3C2-20-AQ | 20 (40 μL) | 200 μL |  |
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| NR3C2-20-DIG | 20 (40 μL) | 200 μL |  |
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| NR3C2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Details
Gene Symbol: NR3C2
Gene Name: Nuclear Receptor Subfamily 3 Group C Member 2
Chromosome: CHR4: 148999914-149363672
Locus: 4q31.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NR3C2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NR3C2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping