NOD1 FISH Probe
The NOD1 FISH probe is designed to hybridize to the NOD1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NOD1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NOD1-20-RE | 20 (40 μL) | 200 μL |  |
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| NOD1-20-GO | 20 (40 μL) | 200 μL |  |
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| NOD1-20-GR | 20 (40 μL) | 200 μL |  |
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| NOD1-20-AQ | 20 (40 μL) | 200 μL |  |
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| NOD1-20-DIG | 20 (40 μL) | 200 μL |  |
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| NOD1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family of proteins. The encoded protein plays a role in innate immunity by acting as a pattern-recognition receptor (PRR) that binds bacterial peptidoglycans and initiates inflammation. This protein has also been implicated in the immune response to viral and parasitic infection. Major structural features of this protein include an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. Mutations in this gene are associated with asthma, inflammatory bowel disease, Behcet disease and sarcoidosis in human patients. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: NOD1
Gene Name: Nucleotide Binding Oligomerization Domain Containing 1
Chromosome: CHR7: 30464142-30518393
Locus: 7p14.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NOD1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NOD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping