NDK A FISH Probe
The NDK A FISH probe is designed to hybridize to the NDK A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
NME1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
NME1-20-RE | 20 (40 μL) | 200 μL | ||
NME1-20-GO | 20 (40 μL) | 200 μL | ||
NME1-20-GR | 20 (40 μL) | 200 μL | ||
NME1-20-AQ | 20 (40 μL) | 200 μL | ||
NME1-20-DIG | 20 (40 μL) | 200 μL | ||
NME1-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NME1
Gene Name: NME/NM23 Nucleoside Diphosphate Kinase 1
Chromosome: CHR17: 49230919-49239450
Locus: 17q21.33
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NDK A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NME1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping