MTTK FISH Probe
The MTTK FISH probe is designed to hybridize to the MTTK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TK2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TK2-20-RE | 20 (40 μL) | 200 μL |  |
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| TK2-20-GO | 20 (40 μL) | 200 μL |  |
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| TK2-20-GR | 20 (40 μL) | 200 μL |  |
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| TK2-20-AQ | 20 (40 μL) | 200 μL |  |
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| TK2-20-DIG | 20 (40 μL) | 200 μL |  |
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| TK2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria. [provided by RefSeq, Dec 2012]
Gene Details
Gene Symbol: TK2
Gene Name: Thymidine Kinase 2, Mitochondrial
Chromosome: CHR16: 66541905-66584315
Locus: 16q21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MTTK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TK2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping