MSH3 FISH Probe
The MSH3 FISH probe is designed to hybridize to the MSH3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MSH3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| MSH3-20-RE | 20 (40 μL) | 200 μL |  |
|
| MSH3-20-GO | 20 (40 μL) | 200 μL |  |
|
| MSH3-20-GR | 20 (40 μL) | 200 μL |  |
|
| MSH3-20-AQ | 20 (40 μL) | 200 μL |  |
|
| MSH3-20-DIG | 20 (40 μL) | 200 μL |  |
|
| MSH3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011]
Gene Details
Gene Symbol: MSH3
Gene Name: MutS Homolog 3
Chromosome: CHR5: 79950293-80172634
Locus: 5q14.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: MSH3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MSH3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping