MPZL2 FISH Probe
The MPZL2 FISH probe is designed to hybridize to the MPZL2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MPZL2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MPZL2-20-RE | 20 (40 μL) | 200 μL |  |
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| MPZL2-20-GO | 20 (40 μL) | 200 μL |  |
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| MPZL2-20-GR | 20 (40 μL) | 200 μL |  |
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| MPZL2-20-AQ | 20 (40 μL) | 200 μL |  |
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| MPZL2-20-DIG | 20 (40 μL) | 200 μL |  |
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| MPZL2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MPZL2
Gene Name: Myelin Protein Zero Like 2
Chromosome: CHR11: 118124130-118135251
Locus: 11q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MPZL2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MPZL2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping