MGC:4834 FISH Probe
The MGC:4834 FISH probe is designed to hybridize to the MGC:4834 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RASD2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RASD2-20-RE | 20 (40 μL) | 200 μL |  |
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| RASD2-20-GO | 20 (40 μL) | 200 μL |  |
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| RASD2-20-GR | 20 (40 μL) | 200 μL |  |
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| RASD2-20-AQ | 20 (40 μL) | 200 μL |  |
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| RASD2-20-DIG | 20 (40 μL) | 200 μL |  |
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| RASD2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: RASD2
Gene Name: RASD Family Member 2
Chromosome: CHR22: 35937351-35950045
Locus: 22q12.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MGC:4834 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RASD2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping