MGC:10353 FISH Probe
The MGC:10353 FISH probe is designed to hybridize to the MGC:10353 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRAF1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TRAF1-20-RE | 20 (40 μL) | 200 μL |  |
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| TRAF1-20-GO | 20 (40 μL) | 200 μL |  |
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| TRAF1-20-GR | 20 (40 μL) | 200 μL |  |
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| TRAF1-20-AQ | 20 (40 μL) | 200 μL |  |
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| TRAF1-20-DIG | 20 (40 μL) | 200 μL |  |
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| TRAF1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Details
Gene Symbol: TRAF1
Gene Name: TNF Receptor Associated Factor 1
Chromosome: CHR9: 123664670-123691451
Locus: 9q33.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MGC:10353 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TRAF1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping