MFM8 FISH Probe
The MFM8 FISH probe is designed to hybridize to the MFM8 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PYROXD1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PYROXD1-20-RE | 20 (40 μL) | 200 μL |  |
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| PYROXD1-20-GO | 20 (40 μL) | 200 μL |  |
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| PYROXD1-20-GR | 20 (40 μL) | 200 μL |  |
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| PYROXD1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PYROXD1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PYROXD1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a nuclear-cytoplasmic pyridine nucleotide-disulphide reductase (PNDR). PNDRs are flavoproteins that catalyze the pyridine nucleotide-dependent reduction of thiol residues in other proteins. The encoded protein belongs to the class I pyridine nucleotide-disulphide oxidoreductase family but lacks the C-terminal dimerization domain found in other family members and instead has a C-terminal nitrile reductase domain. It localizes to the nucleus and to striated sarcomeric compartments. Naturally occurring mutations in this gene cause early-onset myopathy with internalized nuclei and myofibrillar disorganization. A pseudogene of this gene has been defined on chromosome 11. [provided by RefSeq, Apr 2017]
Gene Details
Gene Symbol: PYROXD1
Gene Name: Pyridine Nucleotide-disulphide Oxidoreductase Domain 1
Chromosome: CHR12: 21590537-21624182
Locus: 12p12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MFM8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PYROXD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping