SEARCH OUR PRODUCT CATALOG

MC1-R FISH Probe

The MC1-R FISH probe is designed to hybridize to the MC1-R gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MC1R-20-OR  (Standard Design) 20 (40 μL) 200 μL
MC1R-20-RE 20 (40 μL) 200 μL
MC1R-20-GO 20 (40 μL) 200 μL
MC1R-20-GR 20 (40 μL) 200 μL
MC1R-20-AQ 20 (40 μL) 200 μL
MC1R-20-DIG 20 (40 μL) 200 μL
MC1R-20-BIO 20 (40 μL) 200 μL

Gene Summary

This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: MC1R

Gene Name: Melanocortin 1 Receptor

Chromosome: CHR16: 89984286-89987385

Locus: 16q24.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: MC1-R FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: MC1R-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping