MAPKAPK3 FISH Probe
The MAPKAPK3 FISH probe is designed to hybridize to the MAPKAPK3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAPKAPK3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MAPKAPK3-20-RE | 20 (40 μL) | 200 μL |  |
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| MAPKAPK3-20-GO | 20 (40 μL) | 200 μL |  |
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| MAPKAPK3-20-GR | 20 (40 μL) | 200 μL |  |
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| MAPKAPK3-20-AQ | 20 (40 μL) | 200 μL |  |
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| MAPKAPK3-20-DIG | 20 (40 μL) | 200 μL |  |
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| MAPKAPK3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
Gene Details
Gene Symbol: MAPKAPK3
Gene Name: Mitogen-activated Protein Kinase-activated Protein Kinase 3
Chromosome: CHR3: 50649292-50686728
Locus: 3p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MAPKAPK3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAPKAPK3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping