MAP2K3 FISH Probe
The MAP2K3 FISH probe is designed to hybridize to the MAP2K3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAP2K3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| MAP2K3-20-RE | 20 (40 μL) | 200 μL |  |
|
| MAP2K3-20-GO | 20 (40 μL) | 200 μL |  |
|
| MAP2K3-20-GR | 20 (40 μL) | 200 μL |  |
|
| MAP2K3-20-AQ | 20 (40 μL) | 200 μL |  |
|
| MAP2K3-20-DIG | 20 (40 μL) | 200 μL |  |
|
| MAP2K3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MAP2K3
Gene Name: Mitogen-activated Protein Kinase Kinase 3
Chromosome: CHR17: 21187967-21218551
Locus: 17p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: MAP2K3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAP2K3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping