MAP2K2 FISH Probe
The MAP2K2 FISH probe is designed to hybridize to the MAP2K2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAP2K2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MAP2K2-20-RE | 20 (40 μL) | 200 μL |  |
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| MAP2K2-20-GO | 20 (40 μL) | 200 μL |  |
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| MAP2K2-20-GR | 20 (40 μL) | 200 μL |  |
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| MAP2K2-20-AQ | 20 (40 μL) | 200 μL |  |
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| MAP2K2-20-DIG | 20 (40 μL) | 200 μL |  |
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| MAP2K2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MAP2K2
Gene Name: Mitogen-activated Protein Kinase Kinase 2
Chromosome: CHR19: 4090319-4124126
Locus: 19p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MAP2K2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAP2K2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping