MANF FISH Probe
The MANF FISH probe is designed to hybridize to the MANF gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MANF-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MANF-20-RE | 20 (40 μL) | 200 μL |  |
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| MANF-20-GO | 20 (40 μL) | 200 μL |  |
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| MANF-20-GR | 20 (40 μL) | 200 μL |  |
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| MANF-20-AQ | 20 (40 μL) | 200 μL |  |
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| MANF-20-DIG | 20 (40 μL) | 200 μL |  |
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| MANF-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. [provided by RefSeq, Apr 2014]
Gene Details
Gene Symbol: MANF
Gene Name: Mesencephalic Astrocyte Derived Neurotrophic Factor
Chromosome: CHR3: 51422691-51426828
Locus: 3p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MANF FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MANF-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping