MACS FISH Probe
The MACS FISH probe is designed to hybridize to the MACS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RIN2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RIN2-20-RE | 20 (40 μL) | 200 μL |  |
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| RIN2-20-GO | 20 (40 μL) | 200 μL |  |
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| RIN2-20-GR | 20 (40 μL) | 200 μL |  |
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| RIN2-20-AQ | 20 (40 μL) | 200 μL |  |
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| RIN2-20-DIG | 20 (40 μL) | 200 μL |  |
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| RIN2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
Gene Details
Gene Symbol: RIN2
Gene Name: Ras And Rab Interactor 2
Chromosome: CHR20: 19867164-19983103
Locus: 20p11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MACS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RIN2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping