M FISH Probe
The M FISH probe is designed to hybridize to the M gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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AMH-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
AMH-20-RE | 20 (40 μL) | 200 μL | ||
AMH-20-GO | 20 (40 μL) | 200 μL | ||
AMH-20-GR | 20 (40 μL) | 200 μL | ||
AMH-20-AQ | 20 (40 μL) | 200 μL | ||
AMH-20-DIG | 20 (40 μL) | 200 μL | ||
AMH-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]
Gene Details
Gene Symbol: AMH
Gene Name: Anti-Mullerian Hormone
Chromosome: CHR19: 2249112-2252072
Locus: 19p13.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: M FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AMH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping