LZTS2 FISH Probe
The LZTS2 FISH probe is designed to hybridize to the LZTS2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LZTS2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LZTS2-20-RE | 20 (40 μL) | 200 μL |  |
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| LZTS2-20-GO | 20 (40 μL) | 200 μL |  |
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| LZTS2-20-GR | 20 (40 μL) | 200 μL |  |
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| LZTS2-20-AQ | 20 (40 μL) | 200 μL |  |
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| LZTS2-20-DIG | 20 (40 μL) | 200 μL |  |
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| LZTS2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: LZTS2
Gene Name: Leucine Zipper Tumor Suppressor 2
Chromosome: CHR10: 102756863-102767593
Locus: 10q24.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LZTS2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LZTS2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping