LYGDI FISH Probe
The LYGDI FISH probe is designed to hybridize to the LYGDI gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGDIB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ARHGDIB-20-RE | 20 (40 μL) | 200 μL |  |
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| ARHGDIB-20-GO | 20 (40 μL) | 200 μL |  |
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| ARHGDIB-20-GR | 20 (40 μL) | 200 μL |  |
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| ARHGDIB-20-AQ | 20 (40 μL) | 200 μL |  |
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| ARHGDIB-20-DIG | 20 (40 μL) | 200 μL |  |
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| ARHGDIB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010]
Gene Details
Gene Symbol: ARHGDIB
Gene Name: Rho GDP Dissociation Inhibitor Beta
Chromosome: CHR12: 15094949-15114562
Locus: 12p12.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LYGDI FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ARHGDIB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping