LOXL1 FISH Probe
The LOXL1 FISH probe is designed to hybridize to the LOXL1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LOXL1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LOXL1-20-RE | 20 (40 μL) | 200 μL |  |
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| LOXL1-20-GO | 20 (40 μL) | 200 μL |  |
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| LOXL1-20-GR | 20 (40 μL) | 200 μL |  |
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| LOXL1-20-AQ | 20 (40 μL) | 200 μL |  |
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| LOXL1-20-DIG | 20 (40 μL) | 200 μL |  |
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| LOXL1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: LOXL1
Gene Name: Lysyl Oxidase Like 1
Chromosome: CHR15: 74218788-74244478
Locus: 15q24.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LOXL1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LOXL1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping