LOT1 FISH Probe
The LOT1 FISH probe is designed to hybridize to the LOT1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLAGL1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PLAGL1-20-RE | 20 (40 μL) | 200 μL |  |
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| PLAGL1-20-GO | 20 (40 μL) | 200 μL |  |
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| PLAGL1-20-GR | 20 (40 μL) | 200 μL |  |
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| PLAGL1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PLAGL1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PLAGL1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: PLAGL1
Gene Name: PLAG1 Like Zinc Finger 1
Chromosome: CHR6: 144261436-144385735
Locus: 6q24.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LOT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLAGL1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping