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LON FISH Probe

The LON FISH probe is designed to hybridize to the LON gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
LONP1-20-OR  (Standard Design) 20 (40 μL) 200 μL
LONP1-20-RE 20 (40 μL) 200 μL
LONP1-20-GO 20 (40 μL) 200 μL
LONP1-20-GR 20 (40 μL) 200 μL
LONP1-20-AQ 20 (40 μL) 200 μL
LONP1-20-DIG 20 (40 μL) 200 μL
LONP1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]

Gene Details

Gene Symbol: LONP1

Gene Name: Lon Peptidase 1, Mitochondrial

Chromosome: CHR19: 5691844-5720176

Locus: 19p13.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: LON FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: LONP1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping