LDB3-1 FISH Probe
The LDB3-1 FISH probe is designed to hybridize to the LDB3-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LDB3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LDB3-20-RE | 20 (40 μL) | 200 μL |  |
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| LDB3-20-GO | 20 (40 μL) | 200 μL |  |
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| LDB3-20-GR | 20 (40 μL) | 200 μL |  |
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| LDB3-20-AQ | 20 (40 μL) | 200 μL |  |
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| LDB3-20-DIG | 20 (40 μL) | 200 μL |  |
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| LDB3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq, Jan 2010]
Gene Details
Gene Symbol: LDB3
Gene Name: LIM Domain Binding 3
Chromosome: CHR10: 88428205-88495824
Locus: 10q23.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LDB3-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LDB3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping