LCK FISH Probe
The LCK FISH probe is designed to hybridize to the LCK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LCK-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LCK-20-RE | 20 (40 μL) | 200 μL |  |
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| LCK-20-GO | 20 (40 μL) | 200 μL |  |
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| LCK-20-GR | 20 (40 μL) | 200 μL |  |
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| LCK-20-AQ | 20 (40 μL) | 200 μL |  |
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| LCK-20-DIG | 20 (40 μL) | 200 μL |  |
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| LCK-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016]
Gene Details
Gene Symbol: LCK
Gene Name: LCK Proto-oncogene, Src Family Tyrosine Kinase
Chromosome: CHR1: 32716839-32751766
Locus: 1p35.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LCK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LCK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping