LAIR-1 FISH Probe
The LAIR-1 FISH probe is designed to hybridize to the LAIR-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LAIR1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LAIR1-20-RE | 20 (40 μL) | 200 μL |  |
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| LAIR1-20-GO | 20 (40 μL) | 200 μL |  |
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| LAIR1-20-GR | 20 (40 μL) | 200 μL |  |
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| LAIR1-20-AQ | 20 (40 μL) | 200 μL |  |
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| LAIR1-20-DIG | 20 (40 μL) | 200 μL |  |
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| LAIR1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Details
Gene Symbol: LAIR1
Gene Name: Leukocyte Associated Immunoglobulin Like Receptor 1
Chromosome: CHR19: 54865234-54876721
Locus: 19q13.42
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LAIR-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LAIR1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping