L2 FISH Probe
The L2 FISH probe is designed to hybridize to the L2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PPFIBP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PPFIBP1-20-RE | 20 (40 μL) | 200 μL |  |
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| PPFIBP1-20-GO | 20 (40 μL) | 200 μL |  |
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| PPFIBP1-20-GR | 20 (40 μL) | 200 μL |  |
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| PPFIBP1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PPFIBP1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PPFIBP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PPFIBP1
Gene Name: PPFIA Binding Protein 1
Chromosome: CHR12: 27677044-27848497
Locus: 12p11.23-p11.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: L2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PPFIBP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping