KV7.2 FISH Probe
The KV7.2 FISH probe is designed to hybridize to the KV7.2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KCNQ2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KCNQ2-20-RE | 20 (40 μL) | 200 μL |  |
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| KCNQ2-20-GO | 20 (40 μL) | 200 μL |  |
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| KCNQ2-20-GR | 20 (40 μL) | 200 μL |  |
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| KCNQ2-20-AQ | 20 (40 μL) | 200 μL |  |
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| KCNQ2-20-DIG | 20 (40 μL) | 200 μL |  |
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| KCNQ2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: KCNQ2
Gene Name: Potassium Voltage-gated Channel Subfamily Q Member 2
Chromosome: CHR20: 62037541-62103993
Locus: 20q13.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KV7.2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KCNQ2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping