KPM FISH Probe
The KPM FISH probe is designed to hybridize to the KPM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LATS2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LATS2-20-RE | 20 (40 μL) | 200 μL |  |
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| LATS2-20-GO | 20 (40 μL) | 200 μL |  |
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| LATS2-20-GR | 20 (40 μL) | 200 μL |  |
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| LATS2-20-AQ | 20 (40 μL) | 200 μL |  |
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| LATS2-20-DIG | 20 (40 μL) | 200 μL |  |
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| LATS2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: LATS2
Gene Name: Large Tumor Suppressor Kinase 2
Chromosome: CHR13: 21547175-21635722
Locus: 13q12.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KPM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LATS2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping