KCNQ4 FISH Probe
The KCNQ4 FISH probe is designed to hybridize to the KCNQ4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KCNQ4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KCNQ4-20-RE | 20 (40 μL) | 200 μL |  |
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| KCNQ4-20-GO | 20 (40 μL) | 200 μL |  |
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| KCNQ4-20-GR | 20 (40 μL) | 200 μL |  |
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| KCNQ4-20-AQ | 20 (40 μL) | 200 μL |  |
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| KCNQ4-20-DIG | 20 (40 μL) | 200 μL |  |
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| KCNQ4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: KCNQ4
Gene Name: Potassium Voltage-gated Channel Subfamily Q Member 4
Chromosome: CHR1: 41249683-41306124
Locus: 1p34.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KCNQ4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KCNQ4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping