ITPR2 FISH Probe
The ITPR2 FISH probe is designed to hybridize to the ITPR2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITPR2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ITPR2-20-RE | 20 (40 μL) | 200 μL |  |
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| ITPR2-20-GO | 20 (40 μL) | 200 μL |  |
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| ITPR2-20-GR | 20 (40 μL) | 200 μL |  |
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| ITPR2-20-AQ | 20 (40 μL) | 200 μL |  |
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| ITPR2-20-DIG | 20 (40 μL) | 200 μL |  |
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| ITPR2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. This protein is a type 2 receptor that consists of a cytoplasmic amino-terminus that binds inositol triphosphate, six membrane-spanning helices that contribute to the ion pore, and a short cytoplasmic carboxy-terminus. A mutation in this gene has been associated with anhidrosis, suggesting that intracellular calcium release mediated by this protein is required for eccrine sweat production. [provided by RefSeq, Apr 2015]
Gene Details
Gene Symbol: ITPR2
Gene Name: Inositol 1,4,5-trisphosphate Receptor Type 2
Chromosome: CHR12: 26488284-26986131
Locus: 12p11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ITPR2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ITPR2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping