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ISG43 FISH Probe

The ISG43 FISH probe is designed to hybridize to the ISG43 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
USP18-20-OR  (Standard Design) 20 (40 μL) 200 μL
USP18-20-RE 20 (40 μL) 200 μL
USP18-20-GO 20 (40 μL) 200 μL
USP18-20-GR 20 (40 μL) 200 μL
USP18-20-AQ 20 (40 μL) 200 μL
USP18-20-DIG 20 (40 μL) 200 μL
USP18-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011]

Gene Details

Gene Symbol: USP18

Gene Name: Ubiquitin Specific Peptidase 18

Chromosome: CHR22: 18632757-18660162

Locus: 22q11.21

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ISG43 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: USP18-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping