ING3 FISH Probe
The ING3 FISH probe is designed to hybridize to the ING3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ING3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ING3-20-RE | 20 (40 μL) | 200 μL |  |
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| ING3-20-GO | 20 (40 μL) | 200 μL |  |
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| ING3-20-GR | 20 (40 μL) | 200 μL |  |
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| ING3-20-AQ | 20 (40 μL) | 200 μL |  |
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| ING3-20-DIG | 20 (40 μL) | 200 μL |  |
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| ING3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ING3
Gene Name: Inhibitor Of Growth Family Member 3
Chromosome: CHR7: 120590816-120615711
Locus: 7q31.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ING3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ING3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping