IL6ST FISH Probe
The IL6ST FISH probe is designed to hybridize to the IL6ST gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL6ST-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IL6ST-20-RE | 20 (40 μL) | 200 μL |  |
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| IL6ST-20-GO | 20 (40 μL) | 200 μL |  |
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| IL6ST-20-GR | 20 (40 μL) | 200 μL |  |
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| IL6ST-20-AQ | 20 (40 μL) | 200 μL |  |
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| IL6ST-20-DIG | 20 (40 μL) | 200 μL |  |
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| IL6ST-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]
Gene Details
Gene Symbol: IL6ST
Gene Name: Interleukin 6 Signal Transducer
Chromosome: CHR5: 55230924-55290821
Locus: 5q11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL6ST FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL6ST-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping