IL10R1 FISH Probe
The IL10R1 FISH probe is designed to hybridize to the IL10R1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL10RA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IL10RA-20-RE | 20 (40 μL) | 200 μL |  |
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| IL10RA-20-GO | 20 (40 μL) | 200 μL |  |
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| IL10RA-20-GR | 20 (40 μL) | 200 μL |  |
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| IL10RA-20-AQ | 20 (40 μL) | 200 μL |  |
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| IL10RA-20-DIG | 20 (40 μL) | 200 μL |  |
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| IL10RA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
Gene Details
Gene Symbol: IL10RA
Gene Name: Interleukin 10 Receptor Subunit Alpha
Chromosome: CHR11: 117857105-117872199
Locus: 11q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL10R1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL10RA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping