IL-17RC FISH Probe
The IL-17RC FISH probe is designed to hybridize to the IL-17RC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL17RC-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IL17RC-20-RE | 20 (40 μL) | 200 μL |  |
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| IL17RC-20-GO | 20 (40 μL) | 200 μL |  |
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| IL17RC-20-GR | 20 (40 μL) | 200 μL |  |
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| IL17RC-20-AQ | 20 (40 μL) | 200 μL |  |
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| IL17RC-20-DIG | 20 (40 μL) | 200 μL |  |
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| IL17RC-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: IL17RC
Gene Name: Interleukin 17 Receptor C
Chromosome: CHR3: 9958757-9975305
Locus: 3p25.3-p24.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL-17RC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL17RC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping