IFPS FISH Probe
The IFPS FISH probe is designed to hybridize to the IFPS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FLG2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FLG2-20-RE | 20 (40 μL) | 200 μL |  |
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| FLG2-20-GO | 20 (40 μL) | 200 μL |  |
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| FLG2-20-GR | 20 (40 μL) | 200 μL |  |
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| FLG2-20-AQ | 20 (40 μL) | 200 μL |  |
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| FLG2-20-DIG | 20 (40 μL) | 200 μL |  |
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| FLG2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The filaggrin-like protein encoded by this gene is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: FLG2
Gene Name: Filaggrin Family Member 2
Chromosome: CHR1: 152321212-152332482
Locus: 1q21.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IFPS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FLG2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping