IDDM2 FISH Probe
The IDDM2 FISH probe is designed to hybridize to the IDDM2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| INS-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| INS-20-RE | 20 (40 μL) | 200 μL |  |
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| INS-20-GO | 20 (40 μL) | 200 μL |  |
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| INS-20-GR | 20 (40 μL) | 200 μL |  |
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| INS-20-AQ | 20 (40 μL) | 200 μL |  |
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| INS-20-DIG | 20 (40 μL) | 200 μL |  |
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| INS-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Gene Details
Gene Symbol: INS
Gene Name: Insulin
Chromosome: CHR11: 2181008-2182439
Locus: 11p15.5
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IDDM2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: INS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping