HSPC275 FISH Probe
The HSPC275 FISH probe is designed to hybridize to the HSPC275 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SEC31A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SEC31A-20-RE | 20 (40 μL) | 200 μL |  |
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| SEC31A-20-GO | 20 (40 μL) | 200 μL |  |
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| SEC31A-20-GR | 20 (40 μL) | 200 μL |  |
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| SEC31A-20-AQ | 20 (40 μL) | 200 μL |  |
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| SEC31A-20-DIG | 20 (40 μL) | 200 μL |  |
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| SEC31A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: SEC31A
Gene Name: SEC31 Homolog A, COPII Coat Complex Component
Chromosome: CHR4: 83739813-83812419
Locus: 4q21.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HSPC275 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SEC31A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping