HSPC270 FISH Probe
The HSPC270 FISH probe is designed to hybridize to the HSPC270 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MSRB1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MSRB1-20-RE | 20 (40 μL) | 200 μL |  |
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| MSRB1-20-GO | 20 (40 μL) | 200 μL |  |
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| MSRB1-20-GR | 20 (40 μL) | 200 μL |  |
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| MSRB1-20-AQ | 20 (40 μL) | 200 μL |  |
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| MSRB1-20-DIG | 20 (40 μL) | 200 μL |  |
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| MSRB1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the methionine-R-sulfoxide reductase B (MsrB) family. Members of this family function as repair enzymes that protect proteins from oxidative stress by catalyzing the reduction of methionine-R-sulfoxides to methionines. This protein is highly expressed in liver and kidney, and is localized to the nucleus and cytosol. It is the only member of the MsrB family that is a selenoprotein, containing a selenocysteine (Sec) residue at its active site. It also has the highest methionine-R-sulfoxide reductase activity compared to other members containing cysteine in place of Sec. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. A pseudogene of this locus has been identified on chromosome 19. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: MSRB1
Gene Name: Methionine Sulfoxide Reductase B1
Chromosome: CHR16: 1943292-1938232
Locus: 16p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HSPC270 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MSRB1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping