HP-4 FISH Probe
The HP-4 FISH probe is designed to hybridize to the HP-4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DEFA4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DEFA4-20-RE | 20 (40 μL) | 200 μL |  |
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| DEFA4-20-GO | 20 (40 μL) | 200 μL |  |
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| DEFA4-20-GR | 20 (40 μL) | 200 μL |  |
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| DEFA4-20-AQ | 20 (40 μL) | 200 μL |  |
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| DEFA4-20-DIG | 20 (40 μL) | 200 μL |  |
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| DEFA4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014]
Gene Details
Gene Symbol: DEFA4
Gene Name: Defensin Alpha 4
Chromosome: CHR8: 6793344-6795786
Locus: 8p23.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HP-4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DEFA4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping