HMT FISH Probe
The HMT FISH probe is designed to hybridize to the HMT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HNMT-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HNMT-20-RE | 20 (40 μL) | 200 μL |  |
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| HNMT-20-GO | 20 (40 μL) | 200 μL |  |
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| HNMT-20-GR | 20 (40 μL) | 200 μL |  |
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| HNMT-20-AQ | 20 (40 μL) | 200 μL |  |
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| HNMT-20-DIG | 20 (40 μL) | 200 μL |  |
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| HNMT-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: HNMT
Gene Name: Histamine N-methyltransferase
Chromosome: CHR2: 138721807-138773934
Locus: 2q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HMT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HNMT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping