HI-LNC75 FISH Probe
The HI-LNC75 FISH probe is designed to hybridize to the HI-LNC75 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LINC00673-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LINC00673-20-RE | 20 (40 μL) | 200 μL |  |
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| LINC00673-20-GO | 20 (40 μL) | 200 μL |  |
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| LINC00673-20-GR | 20 (40 μL) | 200 μL |  |
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| LINC00673-20-AQ | 20 (40 μL) | 200 μL |  |
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| LINC00673-20-DIG | 20 (40 μL) | 200 μL |  |
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| LINC00673-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene produces a long non-protein coding RNA that is involved in the regulation of gene expression during tumor progression. This transcript can promote cell proliferation in gastric cancer through interaction with enhancer of zeste 2 and other epigenetic suppressors of gene expression, thereby downregulating target genes including Kruppel like factors 2 and 4. This transcript may also act as a tumor suppressor by promoting interaction between protein tyrosine phosphatase, non-receptor type 11 (Ptpn11) and ubiquitin ligase, resulting in degradation of Ptpn11 and lowered oncogenic signalling. Naturally-occurring variation at this locus results in the formation of a binding site for miR-1231, which negatively regulates activity of this transcript. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2017]
Gene Details
Gene Symbol: LINC00673
Gene Name: Long Intergenic Non-protein Coding RNA 673
Chromosome: CHR17: 72592803-72403321
Locus: 17q24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HI-LNC75 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LINC00673-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping