HGK FISH Probe
The HGK FISH probe is designed to hybridize to the HGK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAP4K4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MAP4K4-20-RE | 20 (40 μL) | 200 μL |  |
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| MAP4K4-20-GO | 20 (40 μL) | 200 μL |  |
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| MAP4K4-20-GR | 20 (40 μL) | 200 μL |  |
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| MAP4K4-20-AQ | 20 (40 μL) | 200 μL |  |
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| MAP4K4-20-DIG | 20 (40 μL) | 200 μL |  |
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| MAP4K4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MAP4K4
Gene Name: Mitogen-activated Protein Kinase Kinase Kinase Kinase 4
Chromosome: CHR2: 102314164-102511152
Locus: 2q11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HGK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAP4K4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping