HDAC FISH Probe
The HDAC FISH probe is designed to hybridize to the HDAC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HDAC3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HDAC3-20-RE | 20 (40 μL) | 200 μL |  |
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| HDAC3-20-GO | 20 (40 μL) | 200 μL |  |
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| HDAC3-20-GR | 20 (40 μL) | 200 μL |  |
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| HDAC3-20-AQ | 20 (40 μL) | 200 μL |  |
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| HDAC3-20-DIG | 20 (40 μL) | 200 μL |  |
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| HDAC3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: HDAC3
Gene Name: Histone Deacetylase 3
Chromosome: CHR5: 141000442-141016423
Locus: 5q31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HDAC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HDAC3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping