GRIN2B FISH Probe
The GRIN2B FISH probe is designed to hybridize to the GRIN2B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GRIN2B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GRIN2B-20-RE | 20 (40 μL) | 200 μL |  |
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| GRIN2B-20-GO | 20 (40 μL) | 200 μL |  |
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| GRIN2B-20-GR | 20 (40 μL) | 200 μL |  |
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| GRIN2B-20-AQ | 20 (40 μL) | 200 μL |  |
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| GRIN2B-20-DIG | 20 (40 μL) | 200 μL |  |
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| GRIN2B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: GRIN2B
Gene Name: Glutamate Ionotropic Receptor NMDA Type Subunit 2B
Chromosome: CHR12: 13714409-14133022
Locus: 12p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GRIN2B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GRIN2B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping