GOK FISH Probe
The GOK FISH probe is designed to hybridize to the GOK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STIM1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| STIM1-20-RE | 20 (40 μL) | 200 μL |  |
|
| STIM1-20-GO | 20 (40 μL) | 200 μL |  |
|
| STIM1-20-GR | 20 (40 μL) | 200 μL |  |
|
| STIM1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| STIM1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| STIM1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Gene Details
Gene Symbol: STIM1
Gene Name: Stromal Interaction Molecule 1
Chromosome: CHR11: 3876932-4114440
Locus: 11p15.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: GOK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: STIM1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping