GNRHR FISH Probe
The GNRHR FISH probe is designed to hybridize to the GNRHR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GNRHR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GNRHR-20-RE | 20 (40 μL) | 200 μL |  |
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| GNRHR-20-GO | 20 (40 μL) | 200 μL |  |
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| GNRHR-20-GR | 20 (40 μL) | 200 μL |  |
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| GNRHR-20-AQ | 20 (40 μL) | 200 μL |  |
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| GNRHR-20-DIG | 20 (40 μL) | 200 μL |  |
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| GNRHR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GNRHR
Gene Name: Gonadotropin Releasing Hormone Receptor
Chromosome: CHR4: 68603098-68621804
Locus: 4q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GNRHR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GNRHR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping