GDNFR FISH Probe
The GDNFR FISH probe is designed to hybridize to the GDNFR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GFRA1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| GFRA1-20-RE | 20 (40 μL) | 200 μL |  |
|
| GFRA1-20-GO | 20 (40 μL) | 200 μL |  |
|
| GFRA1-20-GR | 20 (40 μL) | 200 μL |  |
|
| GFRA1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| GFRA1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| GFRA1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: GFRA1
Gene Name: GDNF Family Receptor Alpha 1
Chromosome: CHR10: 117816441-118033126
Locus: 10q25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: GDNFR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GFRA1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping