FZD6 FISH Probe
The FZD6 FISH probe is designed to hybridize to the FZD6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FZD6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FZD6-20-RE | 20 (40 μL) | 200 μL |  |
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| FZD6-20-GO | 20 (40 μL) | 200 μL |  |
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| FZD6-20-GR | 20 (40 μL) | 200 μL |  |
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| FZD6-20-AQ | 20 (40 μL) | 200 μL |  |
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| FZD6-20-DIG | 20 (40 μL) | 200 μL |  |
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| FZD6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: FZD6
Gene Name: Frizzled Class Receptor 6
Chromosome: CHR8: 104310660-104345094
Locus: 8q22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FZD6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FZD6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping